As we conduct this exploration of how CBD is beginning to prove itself an important tool for therapy and treatment for those battling Crohn’s disease, keep in mind that about 150,000 people currently suffer from this terrible disease in North America at present.
The disease is marked by features that make it widely compared to ulcerative colitis, given its footprint of gastrointestinal inflammation with particular will affect driven toward the small intestine. In fact, Crohn’s is impossible to understand in terms of deep rooted underlying cause given the multi-factorial genetic derivation involved in the pathogenesis of this excruciating ailment.
Poetry can be either beautiful or tragic. But the most impactful poetry is often the most complex. And so it may be with some of the more rare but nonetheless extraordinary health conditions faced by humans in the world today.
And so, perhaps, may it also be with the range of positive effects that we can trace back to that somewhat miraculous plant from which we derive modern phytocannabinoids.
Understanding Crohn’s Disease
Many of the genes directly involved in the production of Crohn’s disease on a physiological level are also correlated with the body’s normal functionality relative to its internal digestive bacteria. In other words, the human digestive system is not just human – we host an ecosystem in our innards. It’s a team enterprise when you eat a cheeseburger.
To maintain that team spirit, the genes that direct the construction and evolution of our immune systems know to give special allowance for members of the team. After all, it wouldn’t do to have our own T-cell foot soldiers running around pointing guns at our teammates in the gut.
However, when our own immune systems begin to launch warfare against our allies – the bacteria that help us digest our food – it can cause huge problems. And those problems are the essence of Crohn’s disease.
While we don’t understand fully the derivation of this compromised condition, there are many theories. One of the most interesting is the notion that Crohn’s disease is something of a measure of just how far we have strayed in our current habits of culinary choice from the sorts of foods that were integrated into our instinctive menu based on the choices present in our environment of evolutionary adaptation.
In other words, it could be that we suddenly have come up with such weird things to eat – relative to what was present and available for the millions of years it took our species to come to the fore – that there are collateral and unintended consequences that bear upon your internal reality as you gobble down a deep-fried triple bacon burger at the drive-through.
CBD and Crohn’s Disease
Once again, the endocannabinoid system becomes extremely relevant to this conversation. As we have discussed, this system sits at the core of many different regulatory systems that govern so much of the functionality of our current physiology.
This is, as one might expect, why we see such dramatic and game changing impact when we study the effects of administration of CBD on health conditions driven on some level by an imbalance to these basic systems.
Crohn’s disease is another perfect example. This disease plays right at the crossroads of the immune system and the digestive system, both of which demonstrate a huge tie-in to the endocannabinoid system that so dominates regulatory functional governance in the human body.
In this case, the key here is that CBD is understood to actually drive the activity level of gut cells higher so that they produce the proper levels of the proteins that are so often lacking in those suffering from various maladies, Crohn’s disease being a crucial example.
At this point, based on scientific and anecdotal evidence, it would appear to be the case that CBD is an effective natural weapon in the battle against a variety of different conditions centered on gastrointestinal imbalances. Crohn’s disease may well be another excellent case.
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